The signaling response of TLR2 to ligands has all the time been as a homodimer or in heterodimerization with TLR1/TLR6. The Toll/Interleukin-1 Receptor (TIR) domain of the TLR cytoplasmic area regulates the dimerization and interactions with adaptor molecules to construct an lively signaling advanced. To perceive the conservation of functionality of the TLR2-heterodimers between the distantly associated species human(h) and mice(m), the sample of TIR-TIR interplay in heterodimers has been studied by the sequence-structural level of view.
Comparative evaluation of major sequence and structural sample of TLRs(1/2/6) corroborates increased sequence homology between TLR1 and TLR6. Molecular docking evaluation of TLR2-TLR1 and TLR2-TLR6 cytoplasmic dimers in each mouse and human have recognized that for interplay the BB loop/near-BB loop residues of TLR2 are concerned with the near-DD loop of TLR1 and DD loop residues of TLR6 inside the TIR domains, which can trigger to differential signaling.
Molecular dynamics simulation of dimers for each human and mice species acknowledge secure interface between near-BB/BB loop area of TLR2 and discrete near-DD and DD loop area of TLR1 and TLR6 respectively. The noticed dimerization sample in each the species is additional supported by Alanine scanning mutation research. However, Solvent Accessible Surface Area (SASA) of BB and DD loop areas of the cytoplasmic monomers and the heterodimers means that whereas TLR2 BB loop is actively related as the dimer interface with its heterodimer companions in each the species, the DD loop acts as the lively interfacing area in hTLR1 and mTLR6. Communicated by Ramaswamy H. Sarma.
High-capacity poly(<em>2</em>-oxazoline) formulation of <em>TLR</em> 7/eight agonist extends survival in a chemo-insensitive, metastatic mannequin of lung adenocarcinoma
About 40% of sufferers with non-small cell lung most cancers (NSCLC) have stage IV most cancers at the time of analysis. The solely viable therapy choices for metastatic illness are systemic chemotherapy and immunotherapy. Nonetheless, chemoresistance stays a significant trigger of chemotherapy failure. New immunotherapeutic modalities comparable to anti-PD-1 immune checkpoint blockade have proven promise; nevertheless, response to such methods is very variable throughout sufferers.
Here, we present that our distinctive poly(2-oxazoline)-based nanomicellar formulation (PM) of Resiquimod, an imidazoquinoline Toll-like receptor (TLR) 7/eight agonist, had a superior tumor inhibitory impact in a metastatic mannequin of lung adenocarcinoma, relative to anti-PD-1 remedy or platinum-based chemotherapy.
Investigation of the in vivo immune standing following Resiquimod PM therapy confirmed that Resiquimod-based stimulation of antigen-presenting cells in the tumor microenvironment resulted in the mobilization of an antitumor CD8+ immune response. Our research demonstrates the promise of poly(2-oxazoline)-formulated Resiquimod for treating metastatic NSCLC.
β-arrestin <em>2</em> quenches <em>TLR</em> signaling to facilitate the immune evasion of EPEC.
The protein translocated intimin receptor (Tir) from enteropathogenic Escherichia coli shares sequence similarity with the host mobile immunoreceptor tyrosine-based inhibition motifs (ITIMs). The ITIMs of Tir are required for Tir-mediated immune inhibition and evasion of host immune responses. However, the underlying molecular mechanism by which Tir regulates immune inhibition stays unclear.
Here we demonstrated that β-arrestin 2, which is concerned in the G-protein-coupled receptor (GPCR) sign pathway, interacted with Tir in an ITIM-dependent method. For the molecular mechanism, we discovered that β-arrestin 2 enhanced the recruitment of SHP-1 to Tir.
The recruited SHP-1 inhibited Okay63-linked ubiquitination of TRAF6 by dephosphorylating TRAF6 at Tyr288, and inhibited Okay63-linked ubiquitination and phosphorylation of TAK1 by dephosphorylating TAK1 at Tyr206, which reduce off the downstream sign transduction and subsequent cytokine manufacturing. Moreover, the inhibitory impact of Tir on immune responses was diminished in β-arrestin 2-deficient mice and macrophages. These findings recommend that β-arrestin 2 is a key regulator in Tir-mediated immune evasion, which might function a brand new therapeutic goal for bacterial infectious illnesses.
Crocin protects in opposition to cardiotoxicity induced by doxorubicin by <em>TLR</em>-<em>2</em>/NF-κB sign pathway in vivo and vitro.
Doxorubicin (DOX) is broadly used to deal with a number of of tumors, however its scientific trials are allied with some severe antagonistic occasions primarily cardiac useful abnormalities. So the goal of our investigation is to establish the cardioprotective motion of crocin (CRO), a pure compound derived from saffron, in opposition to DOX-induced cardiotoxicity. CRO was injected intraperitoneally (i.p.) to rats for sixconsecutive days and DOX (i.p.) was administered on the fourth day.
H9c2 cells have been handled with DOX for 24 h after being pre-treated by CRO for two h. CROreduced tachycardiaand J-point elevation,decreased the levelsof serum creatine kinase, lactate dehydrogenase,glutamic-oxalacetic transaminase and glutamic-pyruvic transaminase.CRO exerted optimistic impact on DOX-induced ROS productionand adjustments of oxidative stress biomarkers. CRO significantly decreased intracellular Ca2+ focus andincreased mitochondria membrane potentialin H9c2 cells.
CRO additionally resisted the DOX-induced excessive expressionof tumor necrosis factor-αand interleukin-6, inhibitedapoptosisand improved the irregular expression ranges of Bcl-2, Bax and Caspase-Three proteins.CRO clearly restrained DOX-mediatedhigh expression of toll-like receptor-2 (TLR-2) and nuclear issue kappa-B (NF-κB) in ventricular tissue. Inbrief,CRO distinctly restrained DOX-mediated cardiotoxicity by inhibiting oxidative stress, irritation, apoptoticandredressingcardiomyocyte calcium dyshomeostasis and mitochondria injury.These cardioprotective results might berelated intently with the TLR2/NF-κB pathway.
Association of Toll-like receptor (<em>TLR</em>) <em>2</em>, Three and 9 genes polymorphism with prostate most cancers danger in North Indian inhabitants.
Prostate most cancers (PCa) is the commonest most cancers amongst males. It has been recommended that toll like receptors (TLRs) might contribute to PCa pathogenesis by stimulating prostate epithelial cell proliferation in response to infectious stimuli. We carried out case management research to research the genetic variants of TLR2, Three and 9 gene polymorphisms with PCa danger in a North Indian inhabitants. For this research we genotyped age matched, unrelated 195 PCa sufferers and 250 wholesome controls of related ethnicity in a case-control research.
They have been genotyped for TLR2 (-196 to -174 Del), TLR3 (c.1377C/T) [rs3775290] and TLR9 (G2848A) [rs352140] gene polymorphisms utilizing polymerase chain response and restriction fragment size polymorphism technique. Variant allele Del (D) carriers i.e. (ID + DD) of TLR2 (-196 to -174 Del) SNP, demonstrated 1.57 fold elevated danger (p = 0.040; OR = 1.57, 95% CI = 1.02-2.24) as in comparison with Ins (I) allele, suggesting a dominant impact mannequin concerned in the danger of this polymorphism in PCa.
 TLR11 Antibody |
|
3277-002mg |
ProSci |
0.02 mg |
EUR 171.82 |
|
|
|
Description: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
TLR11 Antibody |
|
3277-01mg |
ProSci |
0.1 mg |
EUR 436.42 |
|
|
|
Description: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
TLR11 Antibody |
|
3285-002mg |
ProSci |
0.02 mg |
EUR 171.82 |
|
|
|
Description: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
TLR11 Antibody |
|
3285-01mg |
ProSci |
0.1 mg |
EUR 436.42 |
|
|
|
Description: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. |
 TLR11 antibody |
|
70R-12197 |
Fitzgerald |
100 ug |
EUR 403 |
|
Description: Rabbit polyclonal TLR11 antibody |
 Rabbit Polyclonal antibody Anti-CRBN |
|
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 349 |
 TLR11 siRNA |
|
20-abx936886 |
Abbexa |
|
|
|
|
 TLR11 Peptide |
|
3277P |
ProSci |
0.05 mg |
EUR 164.75 |
|
Description: (CT) TLR11 peptide |
TLR11 Peptide |
|
3285P |
ProSci |
0.05 mg |
EUR 164.75 |
|
Description: (IN) TLR11 peptide |
 TLR11 Blocking Peptide |
|
3931BP-50 |
Biovision |
|
EUR 153 |
TLR11 Blocking Peptide |
|
33R-11005 |
Fitzgerald |
50 ug |
EUR 191 |
|
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TLR11 antibody, catalog no. 70R-12197 |
TLR11 Blocking Peptide |
|
33R-10571 |
Fitzgerald |
50 ug |
EUR 349 |
|
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TLR11 antibody, catalog no. 20R-1761 |
 Mouse TLR11 shRNA Plasmid |
|
20-abx982367 |
Abbexa |
|
|
|
|
 Antibody) Toll-Like Receptor 11 (TLR11) Antibody |
|
abx412039-01mg |
Abbexa |
0.1 mg |
EUR 509 |
|
|
 Polyclonal Goat anti-GST α-form |
|
GST-ANTI-1 |
Detroit R&D |
50 uL |
EUR 280 |
 Polyclonal Goat anti-GST μ-form |
|
GST-ANTI-2 |
Detroit R&D |
50 uL |
EUR 280 |
 Polyclonal Goat anti-GST p-form |
|
GST-ANTI-3 |
Detroit R&D |
50 uL |
EUR 280 |
 (pORF)) Tlr11 ORF Vector (Mouse) (pORF) |
|
ORF059652 |
ABM |
1.0 ug DNA |
EUR 506 |
 (pORF)) Tlr11 ORF Vector (Rat) (pORF) |
|
ORF077754 |
ABM |
1.0 ug DNA |
EUR 506 |
) Tlr11 sgRNA CRISPR Lentivector set (Mouse) |
|
K4253601 |
ABM |
3 x 1.0 ug |
EUR 339 |
) Tlr11 sgRNA CRISPR Lentivector set (Rat) |
|
K6339301 |
ABM |
3 x 1.0 ug |
EUR 339 |
 (Target 1)) Tlr11 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
|
K4253602 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 2)) Tlr11 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
|
K4253603 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 3)) Tlr11 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
|
K4253604 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 1)) Tlr11 sgRNA CRISPR Lentivector (Rat) (Target 1) |
|
K6339302 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 2)) Tlr11 sgRNA CRISPR Lentivector (Rat) (Target 2) |
|
K6339303 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 3)) Tlr11 sgRNA CRISPR Lentivector (Rat) (Target 3) |
|
K6339304 |
ABM |
1.0 ug DNA |
EUR 154 |
 Tlr11 3'UTR Luciferase Stable Cell Line |
|
TU221936 |
ABM |
1.0 ml |
Ask for price |
 Tlr11 3'UTR GFP Stable Cell Line |
|
TU271936 |
ABM |
1.0 ml |
Ask for price |
Tlr11 3'UTR GFP Stable Cell Line |
|
TU170543 |
ABM |
1.0 ml |
Ask for price |
Tlr11 3'UTR Luciferase Stable Cell Line |
|
TU120543 |
ABM |
1.0 ml |
Ask for price |
 (pPB-C-His)) Tlr11 Protein Vector (Mouse) (pPB-C-His) |
|
PV238606 |
ABM |
500 ng |
EUR 1065 |
 (pPB-N-His)) Tlr11 Protein Vector (Mouse) (pPB-N-His) |
|
PV238607 |
ABM |
500 ng |
EUR 1065 |
 (pPM-C-HA)) Tlr11 Protein Vector (Mouse) (pPM-C-HA) |
|
PV238608 |
ABM |
500 ng |
EUR 1065 |
 (pPM-C-His)) Tlr11 Protein Vector (Mouse) (pPM-C-His) |
|
PV238609 |
ABM |
500 ng |
EUR 1065 |
 (pPB-C-His)) Tlr11 Protein Vector (Rat) (pPB-C-His) |
|
PV311014 |
ABM |
500 ng |
EUR 1166 |
 (pPB-N-His)) Tlr11 Protein Vector (Rat) (pPB-N-His) |
|
PV311015 |
ABM |
500 ng |
EUR 1166 |
 (pPM-C-HA)) Tlr11 Protein Vector (Rat) (pPM-C-HA) |
|
PV311016 |
ABM |
500 ng |
EUR 1166 |
 (pPM-C-His)) Tlr11 Protein Vector (Rat) (pPM-C-His) |
|
PV311017 |
ABM |
500 ng |
EUR 1166 |
 Mouse Toll- like receptor 11, Tlr11 ELISA KIT |
|
ELI-52133m |
Lifescience Market |
96 Tests |
EUR 865 |
) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
|
K4253605 |
ABM |
3 x 1.0 ug |
EUR 376 |
) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
|
K6339305 |
ABM |
3 x 1.0 ug |
EUR 376 |
 (Target 1)) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
|
K4253606 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 2)) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
|
K4253607 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 3)) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
|
K4253608 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 1)) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
|
K6339306 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 2)) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
|
K6339307 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 3)) Tlr11 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
|
K6339308 |
ABM |
1.0 ug DNA |
EUR 167 |
 Anti-Anti-SEPT6 antibody antibody |
|
STJ11100949 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
 Anti-Anti-SEPT9 Antibody antibody |
|
STJ111369 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
 Anti-Anti-SEPT4 Antibody antibody |
|
STJ112276 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
 Anti-Anti-SEPT5 Antibody antibody |
|
STJ25477 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
 Anti-Anti-SEPT8 Antibody antibody |
|
STJ25479 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
 Anti-Anti-SEPT7 Antibody antibody |
|
STJ28963 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
Anti-Anti-SEPT7 Antibody antibody |
|
STJ116214 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
Anti-Anti-SEPT8 Antibody antibody |
|
STJ117206 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
 Anti-Anti-SEPT12 Antibody antibody |
|
STJ117759 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. |
 Anti-Anti-SEPT1 antibody antibody |
|
STJ119580 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
Anti-Anti-SEPT5 Antibody antibody |
|
STJ114819 |
St John's Laboratory |
100 µl |
EUR 277 |
|
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
 Anti-Anti-DDB1 Antibody |
|
A00333 |
BosterBio |
100uL |
EUR 455 |
|
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse. |
 ELISA Kit) Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
|
AEA465Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5647.8 |
|
|
|
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
|
AEA465Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 552.76 |
|
|
|
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
|
AEA465Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 746.8 |
|
|
|
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
|
AEA465Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3060.6 |
|
|
|
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
|
4-AEA465Hu |
Cloud-Clone |
-
EUR 5698.00
-
EUR 3011.00
-
EUR 747.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
) ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody) |
|
ELK8071 |
ELK Biotech |
1 plate of 96 wells |
EUR 432 |
|
|
|
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
 Anti-MeCP2 Antibody |
|
M00047-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal MeCP2 Antibody. Validated in IHC, WB and tested in Human, Monkey, Mouse, Rat. |
 Anti-GAPDH Antibody |
|
M00227-4 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal GAPDH Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat. |
 Anti-Vimentin Antibody |
|
M00235-4 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat. |
Anti-Vimentin Antibody |
|
M00235-5 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Vimentin Antibody. Validated in IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat. |
 Anti-CNP Antibody |
|
M01017-2 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal CNP Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
Anti-CNP Antibody |
|
M01017-3 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal CNP Antibody. Validated in IHC, WB and tested in Equine, Pig. |
 Anti-GAP43 Antibody |
|
M01868-3 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat. |
Anti-GAP43 Antibody |
|
M01868-4 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal GAP43 Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat. |
 Anti-GPSN2 Antibody |
|
F08289-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for GPSN2 Antibody (TECR) detection.tested for WB in Human, Mouse, Rat. |
 Anti-Calbindin Antibody |
|
M03047-2 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Calbindin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat. |
 Anti-Fibrillarin Antibody |
|
M03178-4 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Fibrillarin Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Fibrillarin Antibody |
|
M03178-5 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Fibrillarin Antibody. Validated in IF, IHC, WB and tested in Bovine, Chicken, Equine, Human, Mouse, Pig, Rat. |
 Anti-Parvalbumin Antibody |
|
M04041-2 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Parvalbumin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
 Anti-Calretinin Antibody |
|
M04255-3 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
Anti-Calretinin Antibody |
|
M04255-4 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Calretinin Antibody. Validated in IF, IHC, WB and tested in Bovine, Equine, Human, Mouse, Pig, Rat. |
 Anti-Laminin Antibody |
|
M04965 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Laminin Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
 Anti-Secretagogin Antibody |
|
M10629-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Secretagogin Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
Anti-Secretagogin Antibody |
|
M10629-2 |
BosterBio |
100ul |
EUR 397 |
|
Description: Chicken Polyclonal Secretagogin Antibody. Validated in IF, IHC, WB and tested in Bovine, Human, Mouse, Rat. |
 Anti-ATF6 Antibody |
|
PA1011 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-ATF6 Antibody |
|
PA1011-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-ATP5J Antibody |
|
PA1012 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Bax Antibody |
|
PA1013 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-Bax Antibody |
|
PA1013-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-BDNF Antibody |
|
PA1014 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-CCR5 Antibody |
|
PA1016 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-CCR5 Antibody |
|
PA1016-1 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-CCR5 Antibody |
|
PA1016-2 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-CCR7 Antibody |
|
PA1017 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-CD22 Antibody |
|
PA1018 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-CD22 Antibody |
|
PA1018-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-CD40 Antibody |
|
PA1019 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-CD40 Antibody |
|
PA1019-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-CD44 Antibody |
|
PA1021 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-CD44 Antibody |
|
PA1021-1 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-CD44 Antibody |
|
PA1021-2 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-GJB2 Antibody |
|
PA1025 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-CXCR2 Antibody |
|
PA1029 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-dUTPase Antibody |
|
PA1030 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-DUT Antibody |
|
PA1030-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-FGF2 Antibody |
|
PA1032 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-FGF4 Antibody |
|
PA1033 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-GAP43 Antibody |
|
PA1037 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Glast Antibody |
|
PA1038 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-GLUT4 Antibody |
|
PA1039 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-HMGB4 Antibody |
|
PA1042 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-INSL3 Antibody |
|
PA1044 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-KCA3.1 Antibody |
|
PA1047 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-KCNN4 Antibody |
|
PA1047-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-MIF Antibody |
|
PA1052 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-NGF Antibody |
|
PA1056 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-BNIP3 Antibody |
|
PA1057 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-NMDAR2A Antibody |
|
PA1058 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-PMVK Antibody |
|
PA1067 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-AMD1 Antibody |
|
PA1070 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-SOCS1 Antibody |
|
PA1074 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-STAT1 Antibody |
|
PA1075 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-TIMP2 Antibody |
|
PA1076 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-TIMP3 Antibody |
|
PA1077 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-TIMP4 Antibody |
|
PA1078 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-TIMP4 Antibody |
|
PA1078-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-SKP2 Antibody |
|
PA1102 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-FOXL2 Antibody |
|
PA1104 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-STAT3 Antibody |
|
PA1108 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-ICAM1 Antibody |
|
PA1110 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-ICAM1 Antibody |
|
PA1110-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-IFITM1 Antibody |
|
PA1112 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-MMP14 Antibody |
|
PA1115 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Fas Antibody |
|
PA1119 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Glut1 Antibody |
|
PA1120 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-MMP2 Antibody |
|
PA1122-1 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-MMP2 Antibody |
|
PA1122-2 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-MMP16 Antibody |
|
PA1123 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-NPY1R Antibody |
|
PA1130 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-OPCML Antibody |
|
PA1131 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-HRH3 Antibody |
|
PA1204 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-MMP8 Antibody |
|
PA1207 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-FABP4 Antibody |
|
PA1209 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Notch1 Antibody |
|
PA1215 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-FGF8 Antibody |
|
PA1216 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-FGF8 Antibody |
|
PA1216-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-PROM1 Antibody |
|
PA1217 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-PROM1 Antibody |
|
PA1217-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-XAF1 Antibody |
|
PA1218 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Rad51 Antibody |
|
PA1219 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-RUNX2 Antibody |
|
PA1224 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-Glut1 Antibody |
|
PA1229 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-SSX2 Antibody |
|
PA1235 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-CXCR4 Antibody |
|
PA1237 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-SLC10A1 Antibody |
|
PA1238 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-GFAP Antibody |
|
PA1239 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-FGFR2 Antibody |
|
PA1241 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-FGFR2 Antibody |
|
PA1241-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-ROCK2 Antibody |
|
PA1242 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-SCN1B Antibody |
|
PA1244 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-TFPI2 Antibody |
|
PA1248 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-APAF1 Antibody |
|
PA1249 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-APAF1 Antibody |
|
PA1249-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-TNFAIP1 Antibody |
|
PA1305 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-SDHA Antibody |
|
PA1306 |
BosterBio |
100ug/vial |
EUR 334 |
However, variants of TLR3 and 9 gene polymorphisms weren’t related to PCa danger. Our outcomes recommended the low penetrance variant of TLR2 (-196 to -174 Del) to be at elevated PCa danger in North Indian inhabitants. Functional research in ethnically numerous populations might present a extra complete involvement of innate immunity in figuring out the disease-associated variants for PCa etiology.
