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  • by Sue Horton
  • April 7, 2021March 12, 2021

Insight into the sequence-structure relationship of TLR cytoplasm’s Toll/Interleukin-1 receptor domain towards understanding the conserved functionality of TLR 2 heterodimer in mammals

  • Antibodies
Insight into the sequence-structure relationship of TLR cytoplasm's Toll/Interleukin-1 receptor domain towards understanding the conserved functionality of TLR 2 heterodimer in mammals
The signaling response of TLR2 to ligands has all the time been as a homodimer or in heterodimerization with TLR1/TLR6. The Toll/Interleukin-1 Receptor (TIR) domain of the TLR cytoplasmic area regulates the dimerization and interactions with adaptor molecules to construct an lively signaling advanced. To perceive the conservation of functionality of the TLR2-heterodimers between the distantly associated species human(h) and mice(m), the sample of TIR-TIR interplay in heterodimers has been studied by the sequence-structural level of view.
Comparative evaluation of major sequence and structural sample of TLRs(1/2/6) corroborates increased sequence homology between TLR1 and TLR6. Molecular docking evaluation of TLR2-TLR1 and TLR2-TLR6 cytoplasmic dimers in each mouse and human have recognized that for interplay the BB loop/near-BB loop residues of TLR2 are concerned with the near-DD loop of TLR1 and DD loop residues of TLR6 inside the TIR domains, which can trigger to differential signaling.
Molecular dynamics simulation of dimers for each human and mice species acknowledge secure interface between near-BB/BB loop area of TLR2 and discrete near-DD and DD loop area of TLR1 and TLR6 respectively. The noticed dimerization sample in each the species is additional supported by Alanine scanning mutation research. However, Solvent Accessible Surface Area (SASA) of BB and DD loop areas of the cytoplasmic monomers and the heterodimers means that whereas TLR2 BB loop is actively related as the dimer interface with its heterodimer companions in each the species, the DD loop acts as the lively interfacing area in hTLR1 and mTLR6. Communicated by Ramaswamy H. Sarma.

High-capacity poly(<em>2</em>-oxazoline) formulation of <em>TLR</em> 7/eight agonist extends survival in a chemo-insensitive, metastatic mannequin of lung adenocarcinoma

About 40% of sufferers with non-small cell lung most cancers (NSCLC) have stage IV most cancers at the time of analysis. The solely viable therapy choices for metastatic illness are systemic chemotherapy and immunotherapy. Nonetheless, chemoresistance stays a significant trigger of chemotherapy failure. New immunotherapeutic modalities comparable to anti-PD-1 immune checkpoint blockade have proven promise; nevertheless, response to such methods is very variable throughout sufferers.
Here, we present that our distinctive poly(2-oxazoline)-based nanomicellar formulation (PM) of Resiquimod, an imidazoquinoline Toll-like receptor (TLR) 7/eight agonist, had a superior tumor inhibitory impact in a metastatic mannequin of lung adenocarcinoma, relative to anti-PD-1 remedy or platinum-based chemotherapy.
Investigation of the in vivo immune standing following Resiquimod PM therapy confirmed that Resiquimod-based stimulation of antigen-presenting cells in the tumor microenvironment resulted in the mobilization of an antitumor CD8+ immune response. Our research demonstrates the promise of poly(2-oxazoline)-formulated Resiquimod for treating metastatic NSCLC.

β-arrestin <em>2</em> quenches <em>TLR</em> signaling to facilitate the immune evasion of EPEC.

The protein translocated intimin receptor (Tir) from enteropathogenic Escherichia coli shares sequence similarity with the host mobile immunoreceptor tyrosine-based inhibition motifs (ITIMs). The ITIMs of Tir are required for Tir-mediated immune inhibition and evasion of host immune responses. However, the underlying molecular mechanism by which Tir regulates immune inhibition stays unclear.
Here we demonstrated that β-arrestin 2, which is concerned in the G-protein-coupled receptor (GPCR) sign pathway, interacted with Tir in an ITIM-dependent method. For the molecular mechanism, we discovered that β-arrestin 2 enhanced the recruitment of SHP-1 to Tir.
The recruited SHP-1 inhibited Okay63-linked ubiquitination of TRAF6 by dephosphorylating TRAF6 at Tyr288, and inhibited Okay63-linked ubiquitination and phosphorylation of TAK1 by dephosphorylating TAK1 at Tyr206, which reduce off the downstream sign transduction and subsequent cytokine manufacturing. Moreover, the inhibitory impact of Tir on immune responses was diminished in β-arrestin 2-deficient mice and macrophages. These findings recommend that β-arrestin 2 is a key regulator in Tir-mediated immune evasion, which might function a brand new therapeutic goal for bacterial infectious illnesses.
Insight into the sequence-structure relationship of <em>TLR</em> cytoplasm's Toll/Interleukin-1 receptor domain towards understanding the conserved functionality of <em>TLR</em> <em>2</em> heterodimer in mammals

Crocin protects in opposition to cardiotoxicity induced by doxorubicin by <em>TLR</em>-<em>2</em>/NF-κB sign pathway in vivo and vitro.

Doxorubicin (DOX) is broadly used to deal with a number of of tumors, however its scientific trials are allied with some severe antagonistic occasions primarily cardiac useful abnormalities. So the goal of our investigation is to establish the cardioprotective motion of crocin (CRO), a pure compound derived from saffron, in opposition to DOX-induced cardiotoxicity. CRO was injected intraperitoneally (i.p.) to rats for sixconsecutive days and DOX (i.p.) was administered on the fourth day.
H9c2 cells have been handled with DOX for 24 h after being pre-treated by CRO for two h. CROreduced tachycardiaand J-point elevation,decreased the levelsof serum creatine kinase, lactate dehydrogenase,glutamic-oxalacetic transaminase and glutamic-pyruvic transaminase.CRO exerted optimistic impact on DOX-induced ROS productionand adjustments of oxidative stress biomarkers. CRO significantly decreased intracellular Ca2+ focus andincreased mitochondria membrane potentialin H9c2 cells.
CRO additionally resisted the DOX-induced excessive expressionof tumor necrosis factor-αand interleukin-6, inhibitedapoptosisand improved the irregular expression ranges of Bcl-2, Bax and Caspase-Three proteins.CRO clearly restrained DOX-mediatedhigh expression of toll-like receptor-2 (TLR-2) and nuclear issue kappa-B (NF-κB) in ventricular tissue. Inbrief,CRO distinctly restrained DOX-mediated cardiotoxicity by inhibiting oxidative stress, irritation, apoptoticandredressingcardiomyocyte calcium dyshomeostasis and mitochondria injury.These cardioprotective results might berelated intently with the TLR2/NF-κB pathway.

Association of Toll-like receptor (<em>TLR</em>) <em>2</em>, Three and 9 genes polymorphism with prostate most cancers danger in North Indian inhabitants.

Prostate most cancers (PCa) is the commonest most cancers amongst males. It has been recommended that toll like receptors (TLRs) might contribute to PCa pathogenesis by stimulating prostate epithelial cell proliferation in response to infectious stimuli. We carried out case management research to research the genetic variants of TLR2, Three and 9 gene polymorphisms with PCa danger in a North Indian inhabitants. For this research we genotyped age matched, unrelated 195 PCa sufferers and 250 wholesome controls of related ethnicity in a case-control research.
They have been genotyped for TLR2 (-196 to -174 Del), TLR3 (c.1377C/T) [rs3775290] and TLR9 (G2848A) [rs352140] gene polymorphisms utilizing polymerase chain response and restriction fragment size polymorphism technique. Variant allele Del (D) carriers i.e. (ID + DD) of TLR2 (-196 to -174 Del) SNP, demonstrated 1.57 fold elevated danger (p = 0.040; OR = 1.57, 95% CI = 1.02-2.24) as in comparison with Ins (I) allele, suggesting a dominant impact mannequin concerned in the danger of this polymorphism in PCa.

TLR11 Antibody

3277-002mg ProSci 0.02 mg
EUR 206.18
Description: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

TLR11 Antibody

3277-01mg ProSci 0.1 mg
EUR 523.7
Description: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

TLR11 Antibody

24231 SAB 100ul
EUR 479

TLR11 Antibody

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TLR11 Antibody

24234 SAB 100ul
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TLR11 Antibody

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EUR 468

Tlr11 Antibody

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Description: Recombinant Mus musculus Tlr11 protein

Tlr11 Antibody

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Description: Recombinant Mus musculus Tlr11 protein

TLR11 Antibody

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EUR 445

TLR11 Antibody

MBS150758-5x01mg MyBiosource 5x0.1mg
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TLR11 Antibody

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EUR 1965

TLR11 Antibody

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TLR11 Antibody

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TLR11 Antibody

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TLR11 Polyclonal Antibody

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EUR 415

TLR11 Polyclonal Antibody

MBS9237623-5x01mL MyBiosource 5x0.1mL
EUR 1841

Anti-Toll-like receptor 11 TLR11 Antibody

A33174 BosterBio 0.1mg
EUR 449
Description: Boster Bio Anti-Toll-like receptor 11 TLR11 Antibody (Catalog # A33174). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Mouse.

Anti-Toll-Like Receptor 11 (TLR11) Antibody

GWB-517DFF GenWay Biotech 0.1 mg Ask for price

TLR11 Antibody FITC-Conjugated

MBS5400082-01mg MyBiosource 0.1mg
EUR 560

TLR11 Antibody FITC-Conjugated

MBS5400082-5x01mg MyBiosource 5x0.1mg
EUR 2380

TLR11 Antibody Affinity Purified

MBS540124-01mg MyBiosource 0.1mg
EUR 445

TLR11 Antibody Affinity Purified

MBS540124-5x01mg MyBiosource 5x0.1mg
EUR 1855

OAEG01004-100UG - Tlr11 Antibody

OAEG01004-100UG Aviva Systems Biology 100ug
EUR 469

Rabbit Polyclonal TLR11 Antibody

TA306158 Origene Technologies GmbH 100 µg Ask for price

Rabbit Polyclonal TLR11 Antibody

TA306160 Origene Technologies GmbH 100 µg Ask for price

TLR11 Antibody BIOTIN-Conjugated

MBS5400081-01mg MyBiosource 0.1mg
EUR 560

TLR11 Antibody BIOTIN-Conjugated

MBS5400081-5x01mg MyBiosource 5x0.1mg
EUR 2380

Mouse TLR11 Antibody (C-term)

GWB-4F3B6E GenWay Biotech 0.1 mg Ask for price

TLR11 Antibody Antigenic Blocking Peptide

MBS544575-025mg MyBiosource 0.25mg
EUR 280

TLR11 Antibody Antigenic Blocking Peptide

MBS544575-5x025mg MyBiosource 5x0.25mg
EUR 1110

Rabbit anti-Mus musculus (Mouse) Tlr11 Polyclonal Antibody

MBS7199286-INQUIRE MyBiosource INQUIRE Ask for price

Anti Human TLR2 Pab

165782 Antibody Research Corporation 100 µg Ask for price

Anti Human TLR9 Pab

165783 Antibody Research Corporation 100 µg Ask for price

Anti Human TLR4 Pab

111784 Antibody Research Corporation 100 µg Ask for price

Toll-Like Receptor 11 (TLR11) Antibody

abx412039-01mg Abbexa 0.1 mg
EUR 610.8

Toll-Like Receptor 11 (TLR11) Antibody

abx412039-200g Abbexa 200 µg
EUR 437.5

TLR11 Antibody Western Blot Positive Control

MBS543319-5Applications MyBiosource 5Applications
EUR 335

TLR11 Antibody Western Blot Positive Control

MBS543319-5x5Applications MyBiosource 5x5Applications
EUR 1350

Rat Monoclonal anti-mouse TLR11

mAP-0548 Angio Proteomie 50ug
EUR 400

Anti - TLR11 (Toll Like Receptor 11)

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EUR 635

Anti - TLR11 (Toll Like Receptor 11)

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Anti - TLR11 (Toll Like Receptor 11)

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RABBIT ANTI MOUSE TLR11 (C-TERMINAL)

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RABBIT ANTI MOUSE TLR11 (C-TERMINAL)

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Anti - TLR11 (Toll Like Receptor 11) (CT)

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Anti - TLR11 (Toll Like Receptor 11) (CT)

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EUR 2785

TLR11 Peptide

3285P ProSci 0.05 mg
EUR 197.7
Description: (IN) TLR11 peptide

TLR11 Peptide

3277P ProSci 0.05 mg
EUR 197.7
Description: (CT) TLR11 peptide

TLR11 Peptide

MBS151996-005mg MyBiosource 0.05mg
EUR 175

TLR11 Peptide

MBS151996-5x005mg MyBiosource 5x0.05mg
EUR 770

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MBS152110-005mg MyBiosource 0.05mg
EUR 175

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EUR 770

Mouse TLR11 siRNA

20-abx936886 Abbexa
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

TLR11 siRNA (Mouse)

MBS8219700-15nmol MyBiosource 15nmol
EUR 405

TLR11 siRNA (Mouse)

MBS8219700-30nmol MyBiosource 30nmol
EUR 565

TLR11 siRNA (Mouse)

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EUR 2450

Tlr11 (untagged) - Mouse toll-like receptor 11 (Tlr11), (10ug)

MC222669 Origene Technologies GmbH 10 µg Ask for price

TLR11 Blocking Peptide

3931BP-50 Biovision each
EUR 183.6

Tlr11 (GFP-tagged) - Mouse toll-like receptor 11 (Tlr11), (10ug)

MG215375 Origene Technologies GmbH 10 µg Ask for price

Tlr11 (Myc-DDK-tagged) - Mouse toll-like receptor 11 (Tlr11)

MR215375 Origene Technologies GmbH 10 µg Ask for price

Tlr11 (untagged ORF) - Rat toll-like receptor 11 (Tlr11), (10 ug)

RN212179 Origene Technologies GmbH 10 µg Ask for price

Mouse TLR11 shRNA Plasmid

20-abx982367 Abbexa
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Anti-TLR11 Antibody

STJ503275 St John's Laboratory 100 µg
EUR 571.2

Tlr11 (Myc-DDK-tagged ORF) - Rat toll-like receptor 11 (Tlr11), (10 ug)

RR212179 Origene Technologies GmbH 10 µg Ask for price

Tlr11 ORF Vector (Rat) (pORF)

ORF077754 ABM 1.0 ug DNA
EUR 607.2

Lenti ORF clone of Tlr11 (mGFP-tagged) - Mouse toll-like receptor 11 (Tlr11)

MR215375L4 Origene Technologies GmbH 10 µg Ask for price

Tlr11 ORF Vector (Mouse) (pORF)

ORF059652 ABM 1.0 ug DNA
EUR 607.2

Mouse Tlr11 qPCR Primer Pair

QM62094S Beyotime Biotech Inc 200 Tests Ask for price

Anti Bovine Leptin Antibody

111002 Antibody Research Corporation 100 µg Ask for price

Anti Stercobilin Antibody Pab

165755 Antibody Research Corporation 100 µg Ask for price

Lenti ORF clone of Tlr11 (Myc-DDK-tagged) - Mouse toll-like receptor 11 (Tlr11)

MR215375L3 Origene Technologies GmbH 10 µg Ask for price

anti- TLR3 antibody

FNab08726 FN Test 100µg
EUR 658.5
Description: Antibody raised against TLR3

anti- TLR4 antibody

FNab08727 FN Test 100µg
EUR 606.3
Description: Antibody raised against TLR4

anti- TLR5 antibody

FNab08728 FN Test 100µg
EUR 658.5
Description: Antibody raised against TLR5

anti- TLR6 antibody

FNab08729 FN Test 100µg
EUR 658.5
Description: Antibody raised against TLR6

anti- TLR7 antibody

FNab08730 FN Test 100µg
EUR 658.5
Description: Antibody raised against TLR7

anti- TLR2 antibody

FNab09836 FN Test 100µg
EUR 658.5
Description: Antibody raised against TLR2

anti- TLR4 antibody

FNab09837 FN Test 100µg
EUR 658.5
Description: Antibody raised against TLR4

anti- TLR8 antibody

FNab10155 FN Test 100µg
EUR 606.3
Description: Antibody raised against TLR8

anti- TLR2 antibody

LSMab09836 Nova Lifetech 100ug
EUR 325

anti- TLR4 antibody

LSMab09837 Nova Lifetech 100ug
EUR 325

Toll-Like Receptor 11 (TLR11) (IN)

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Toll-like receptor 11 (TLR11) (IN)

MBS395936-01mg MyBiosource 0.1mg
EUR 505

Toll-like receptor 11 (TLR11) (IN)

MBS395936-5x01mg MyBiosource 5x0.1mg
EUR 2125

Anti-TLR11 Antibody FITC

STJ503290 St John's Laboratory 100 µg
EUR 703.2

Anti-TLR11 Antibody BIOTIN

STJ503289 St John's Laboratory 100 µg
EUR 703.2

Tlr11 sgRNA CRISPR Lentivector set (Rat)

K6339301 ABM 3 x 1.0 ug
EUR 406.8

Anti Plant Glycan Antibody [CCRC-M95]

401030 Antibody Research Corporation 100 µg Ask for price

Lenti ORF clone of Tlr11 (mGFP-tagged ORF) - Rat toll-like receptor 11 (Tlr11), (10 ug)

RR212179L4 Origene Technologies GmbH 10 µg Ask for price

Tlr11 sgRNA CRISPR Lentivector set (Mouse)

K4253601 ABM 3 x 1.0 ug
EUR 406.8

Lenti ORF particles, Tlr11 (GFP-tagged) - Mouse toll-like receptor 11 (Tlr11), 200ul, >10^7 TU/mL

MR215375L4V Origene Technologies GmbH 200 µl Ask for price

Lenti ORF clone of Tlr11 (Myc-DDK-tagged ORF) - Rat toll-like receptor 11 (Tlr11), (10 ug)

RR212179L3 Origene Technologies GmbH 10 µg Ask for price

TLR11 (Toll Like Receptor 11) (CT) (AP)

MBS6503114-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (AP)

MBS6503114-5x01mL MyBiosource 5x0.1mL
EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (PE)

MBS6503124-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (PE)

MBS6503124-5x01mL MyBiosource 5x0.1mL
EUR 4080

Tlr11 3'UTR GFP Stable Cell Line

TU271936 ABM 1.0 ml Ask for price

Tlr11 3'UTR GFP Stable Cell Line

TU170543 ABM 1.0 ml Ask for price

TLR11 (Toll Like Receptor 11) (CT) (APC)

MBS6503115-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (APC)

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EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (HRP)

MBS6503118-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (HRP)

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EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (FITC)

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EUR 940

TLR11 (Toll Like Receptor 11) (CT) (FITC)

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EUR 4080

Polyclonal Anti- TLR4 Antibody

GWB-BBP361 GenWay Biotech 0.1 mg Ask for price

Lenti ORF particles, Tlr11 (GFP-tagged ORF) - Rat toll-like receptor 11 (Tlr11), 200ul, >10^7 TU/mL

RR212179L4V Origene Technologies GmbH 200 µl Ask for price

TLR11 (Toll Like Receptor 11) (CT) (Biotin)

MBS6503116-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (Biotin)

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EUR 4080

Tlr11 Protein Vector (Rat) (pPM-C-HA)

PV311016 ABM 500 ng
EUR 1399.2

Tlr11 Protein Vector (Rat) (pPB-C-His)

PV311014 ABM 500 ng
EUR 1399.2

Tlr11 Protein Vector (Rat) (pPB-N-His)

PV311015 ABM 500 ng
EUR 1399.2

Tlr11 Protein Vector (Rat) (pPM-C-His)

PV311017 ABM 500 ng
EUR 1399.2

Lenti ORF particles, Tlr11 (Myc-DDK-tagged) - Mouse toll-like receptor 11 (Tlr11), 200ul, >10^7 TU/mL

MR215375L3V Origene Technologies GmbH 200 µl Ask for price

Tlr11 Protein Vector (Mouse) (pPM-C-HA)

PV238608 ABM 500 ng
EUR 1278

Tlr11 Protein Vector (Mouse) (pPB-C-His)

PV238606 ABM 500 ng
EUR 1278

Tlr11 Protein Vector (Mouse) (pPB-N-His)

PV238607 ABM 500 ng
EUR 1278

Tlr11 Protein Vector (Mouse) (pPM-C-His)

PV238609 ABM 500 ng
EUR 1278

Tlr11 3'UTR Luciferase Stable Cell Line

TU120543 ABM 1.0 ml Ask for price

Tlr11 3'UTR Luciferase Stable Cell Line

TU221936 ABM 1.0 ml Ask for price

TLR11 (Toll Like Receptor 11) (Control Peptide)

MBS658883-005mg MyBiosource 0.05mg
EUR 395

TLR11 (Toll Like Receptor 11) (Control Peptide)

MBS658883-5x005mg MyBiosource 5x0.05mg
EUR 1630

TLR11 (Toll Like Receptor 11) (Control Peptide)

MBS658105-005mg MyBiosource 0.05mg
EUR 395

TLR11 (Toll Like Receptor 11) (Control Peptide)

MBS658105-5x005mg MyBiosource 5x0.05mg
EUR 1630

Tlr11 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6339302 ABM 1.0 ug DNA
EUR 184.8

Tlr11 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6339303 ABM 1.0 ug DNA
EUR 184.8

Tlr11 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6339304 ABM 1.0 ug DNA
EUR 184.8

Tlr11 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4253602 ABM 1.0 ug DNA
EUR 184.8

Tlr11 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4253603 ABM 1.0 ug DNA
EUR 184.8

Tlr11 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4253604 ABM 1.0 ug DNA
EUR 184.8

Lenti ORF particles, Tlr11 (Myc-DDK-tagged ORF) - Rat toll-like receptor 11 (Tlr11), 200ul, >10^7 TU/mL

RR212179L3V Origene Technologies GmbH 200 µl Ask for price

Anti-Mouse CD282/TLR2 Antibody

MBS1569976-01mg MyBiosource 0.1mg
EUR 405

Anti-Mouse CD282/TLR2 Antibody

MBS1569976-5x01mg MyBiosource 5x0.1mg
EUR 1520

Anti-Mouse CD289/TLR9 Antibody

MBS1569568-01mg MyBiosource 0.1mg
EUR 405

Anti-Mouse CD289/TLR9 Antibody

MBS1569568-5x01mg MyBiosource 5x0.1mg
EUR 1520

Anti Mouse E3 Ubiquitin-Protein Ligase MYCBP2 Antibody, Phr1

164056 Antibody Research Corporation 100 µg Ask for price

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 405)

MBS6503119-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 405)

MBS6503119-5x01mL MyBiosource 5x0.1mL
EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 490)

MBS6503120-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 490)

MBS6503120-5x01mL MyBiosource 5x0.1mL
EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 550)

MBS6503121-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 550)

MBS6503121-5x01mL MyBiosource 5x0.1mL
EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 650)

MBS6503122-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 650)

MBS6503122-5x01mL MyBiosource 5x0.1mL
EUR 4080

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 750)

MBS6503123-01mL MyBiosource 0.1mL
EUR 940

TLR11 (Toll Like Receptor 11) (CT) (MaxLight 750)

MBS6503123-5x01mL MyBiosource 5x0.1mL
EUR 4080

Anti-Toll-like receptor 13 TLR13 Antibody

A30430 BosterBio 100ul
EUR 399
Description: Boster Bio Anti-Toll-like receptor 13 TLR13 Antibody catalog # A30430. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Anti-Toll-like Receptor 10 (TLR10) Antibody

GWB-42AA54 GenWay Biotech 0.1 mg Ask for price

Anti-Toll-like receptor 10 TLR10 Antibody

PA1958 BosterBio 100ug/vial
EUR 154
Description: Western blot, 0.1-0.5μg/ml, Human

PE anti-mouse CD282 (TLR2) Antibody

E16FMP282-100U EnoGene 100 μg
EUR 1235
Description: Available in various conjugation types.

Mouse Toll- like receptor 11, Tlr11 ELISA KIT

ELI-52133m Lifescience Market 96 Tests
EUR 1038

Rat Toll-like receptor 11,TLR11 ELISA KIT

E1558Ra-1096T Jiaxing Korain Biotech Ltd (BT Labs) 10*96T
EUR 4122

Rat Toll-like receptor 11,TLR11 ELISA KIT

E1558Ra-48wells Jiaxing Korain Biotech Ltd (BT Labs) 48 wells
EUR 300

Rat Toll-like receptor 11,TLR11 ELISA KIT

E1558Ra-596T Jiaxing Korain Biotech Ltd (BT Labs) 5*96T
EUR 2061

Rat Toll-like receptor 11,TLR11 ELISA KIT

E1558Ra-96wells Jiaxing Korain Biotech Ltd (BT Labs) 96 wells
EUR 458

Rat Toll-like receptor 11,TLR11 ELISA KIT

JOT-EK1558Ra Jotbody 96 wells Ask for price
Description: Rat

Rat Toll-like receptor 11, TLR11 ELISA Kit

MBS1600552-10x96StripWells MyBiosource 10x96-Strip-Wells
EUR 3955

Rat Toll-like receptor 11, TLR11 ELISA Kit

MBS1600552-48StripWells MyBiosource 48-Strip-Wells
EUR 305

Rat Toll-like receptor 11, TLR11 ELISA Kit

MBS1600552-5x96StripWells MyBiosource 5x96-Strip-Wells
EUR 2005

Rat Toll-like receptor 11, TLR11 ELISA Kit

MBS1600552-96StripWells MyBiosource 96-Strip-Wells
EUR 475

Human Toll Like Receptor 11 (TLR11) ELISA Kit

SL3530Hu Sunlong 96 Tests
EUR 468

Anti-Human CD289/TLR9 Antibody (5G5)

MBS1569266-01mg MyBiosource 0.1mg
EUR 405

Anti-Human CD289/TLR9 Antibody (5G5)

MBS1569266-5x01mg MyBiosource 5x0.1mg
EUR 1520

Mouse Toll-like receptor 11 (TLR11) ELISA Kit

abx549850-96tests Abbexa 96 tests
EUR 687.5

Human Toll-like receptor 11,TLR11 ELISA KIT

JOT-EK7018Hu Jotbody 96 wells Ask for price
Description: Human

Human Toll-like receptor 11,TLR11 ELISA KIT

E7018Hu-1096T Jiaxing Korain Biotech Ltd (BT Labs) 10*96T
EUR 4122

Human Toll-like receptor 11,TLR11 ELISA KIT

E7018Hu-48wells Jiaxing Korain Biotech Ltd (BT Labs) 48 wells
EUR 300

Human Toll-like receptor 11,TLR11 ELISA KIT

E7018Hu-596T Jiaxing Korain Biotech Ltd (BT Labs) 5*96T
EUR 2061

Human Toll-like receptor 11,TLR11 ELISA KIT

E7018Hu-96wells Jiaxing Korain Biotech Ltd (BT Labs) 96 wells
EUR 458

Rat Toll Like Receptor 11, TLR11 GENLISA ELISA

KLR1558 Krishgen 1 x 96 wells
EUR 341

Human Toll-like receptor 11, TLR11 ELISA Kit

MBS1608756-10x96StripWells MyBiosource 10x96-Strip-Wells
EUR 3460

Human Toll-like receptor 11, TLR11 ELISA Kit

MBS1608756-48StripWells MyBiosource 48-Strip-Wells
EUR 285

Human Toll-like receptor 11, TLR11 ELISA Kit

MBS1608756-5x96StripWells MyBiosource 5x96-Strip-Wells
EUR 1750

Human Toll-like receptor 11, TLR11 ELISA Kit

MBS1608756-96StripWells MyBiosource 96-Strip-Wells
EUR 425
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However, variants of TLR3 and 9 gene polymorphisms weren’t related to PCa danger. Our outcomes recommended the low penetrance variant of TLR2 (-196 to -174 Del) to be at elevated PCa danger in North Indian inhabitants. Functional research in ethnically numerous populations might present a extra complete involvement of innate immunity in figuring out the disease-associated variants for PCa etiology.
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  • Curcumin attenuates Concanavalin A-induced liver injury in mice by inhibition of Toll-like receptor (TLR) 2, TLR4 and TLR9 expression.
  • Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR–2 signaling.
  • Systemic isotretinoin therapy normalizes exaggerated TLR–2-mediated innate immune responses in acne patients.
  • Insight into the sequence-structure relationship of TLR cytoplasm’s Toll/Interleukin-1 receptor domain towards understanding the conserved functionality of TLR 2 heterodimer in mammals
  • In silico analyses on the comparative sensing of SARS-CoV-2 mRNA by the intracellular TLRs of human

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