Systemic Dermatitis Model Mice Exhibit Atrophy of Visceral Adipose Tissue and Increase Stromal Cells via Skin-Derived Inflammatory Cytokines.

: Adipose tissue (AT) is the largest endocrine organ, producing bioactive products called adipocytokines, which regulate several metabolic pathways, especially in inflammatory conditions.

On the other hand, there is evidence that chronic inflammatory skin disease is closely associated with vascular sclerotic changes, cardiomegaly, and severe systemic amyloidosis in multiple organs. In psoriasis, a common chronic intractable inflammatory skin disease, several studies have shown that adipokine levels are associated with disease severity.

Chronic skin disease is also associated with metabolic syndrome, including abnormal tissue remodeling; however, the mechanism is still unclear. We addressed this problem using keratin 14-specific caspase-1 overexpressing transgenic (KCASP1Tg) mice with severe erosive dermatitis from 8 weeks of age, followed by re-epithelization.

The whole body and gonadal white AT (GWAT) weights were decreased. Each adipocyte was large in number, small in size and irregularly shaped; abundant inflammatory cells, including activated CD4+ or CD8+ T cells and toll–like receptor 4/CD11b-positive activated monocytes, infiltrated into the GWAT.

We assumed that inflammatory cytokine production in skin lesions was the key factor for this lymphocyte/monocyte activation and AT dysregulation. We tested our hypothesis that the AT in a mouse dermatitis model shows an impaired thermogenesis ability due to systemic inflammation. After exposure to 4 °C, the mRNA expression of the thermogenic gene uncoupling protein 1 in adipocytes was elevated; however, the body temperature of the KCASP1Tg mice decreased rapidly, revealing an impaired thermogenesis ability of the AT due to atrophy.

necrosis factor (TNF)-α, IL-1β and interferon (INF)-γ levels were significantly increased in KCASP1Tg mouse ear skin lesions. To investigate the direct effects of these cytokines, BL/6 wild mice were administered intraperitoneal TNF-α, IL-1β and INF-γ injections, which resulted in small adipocytes with abundant stromal cell infiltration, suggesting those cytokines have a synergistic effect on adipocytes.

The systemic dermatitis model mice showed atrophy of AT and increased stromal cells. These findings were reproducible by the intraperitoneal administration of inflammatory cytokines whose production was increased in inflamed skin lesions.

HSP70 ELISA Kit
SKT-105-480	Stressmarq	5 plates of 96 wells	EUR 2260
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Cell Lysates, Tissue, Serum, Urine samples from Human, Goat, Dog

HSC70 ELISA Kit
SKT-106-480	Stressmarq	5 plates of 96 wells	EUR 2836
Description: Sandwich ELISA kit used for quantitate HSC70 concentration in Cell Lysates, Tissue, Serum, Whole Blood samples from Human, Avian

HSP90 alpha ELISA Kit
SKT-107-480	Stressmarq	5 plates of 96 wells	EUR 2702
Description: Sandwich ELISA kit used for quantitate HSP90 alpha concentration in Cell Lysates, Tissue, Serum, Whole Blood samples from Human, Goat, Avian

HSP27 ELISA Kit
SKT-109-480	Stressmarq	5 plates of 96 wells	EUR 2277
Description: Sandwich ELISA kit used for quantitate HSP27 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human

HSP60 ELISA Kit
SKT-110-480	Stressmarq	5 plates of 96 wells	EUR 2277
Description: Sandwich ELISA kit used for quantitate HSP60 concentration in Cell Lysates, Tissue, Serum samples from Human

HO-1 ELISA Kit
SKT-111-480	Stressmarq	5 plates of 96 wells	EUR 2277
Description: Sandwich ELISA kit used for quantitate HO-1 concentration in Cell Lysates, Tissue, Serum, Cyst fluid samples from Human, Rat

HSP65 ELISA Kit
SKT-113-480	Stressmarq	5 plates of 96 wells	EUR 2478
Description: Sandwich ELISA kit used for quantitate M bovis/M tuberculosum HSP65 concentration in human samples in Cell Lysates, Tissue, Serum samples from M bovis, M tuberculosum

Alpha B Crystallin ELISA Kit
SKT-123-480	Stressmarq	5 plates of 96 wells	EUR 2836
Description: Sandwich ELISA kit used for quantitate alpha B crystallin concentration in Cell Lysates, Tissue, Serum samples from Human

HSP70 ELISA Kit (PLANT)
SKT-124-480	Stressmarq	5 plates of 96 wells	EUR 2836
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Plant extract, Cell Lysates, Tissue, Serum, Plasma samples from Plant, Human

Nitrotyrosine ELISA Kit
SKT-126-480	Stressmarq	5 plates of 96 wells	EUR 1747
Description: Competitive ELISA kit used for quantitate Nitrotyrosine in Plasma, Serum, Cell Lysates, Urine samples from all species

Rat GRP78 ELISA Kit
SKT-137-480	Stressmarq	5 plates of 96 wells	EUR 2474
Description: Sandwich ELISA kit used for quantitate GRP78 concentration in rat samples in Tissue samples from Rat

Dibromo-tyrosine ELISA Kit
SKT-140-480	Stressmarq	5 plates of 96 wells	EUR 2195
Description: Competitive ELISA kit used to quantify free and protein-bound 3,5-dibromotyrosine in Plasma, Urine samples from all species

HSP70 ELISA Kit (High-Sensitivity)
SKT-108-96	Stressmarq	1 plate of 96 wells	EUR 685
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse

Mouse SKT shRNA Plasmid
20-abx980555	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg

JW 480
B5556-10	ApexBio	10 mg	EUR 167

JW 480
B5556-25	ApexBio	25 mg	EUR 325

JW 480
B5556-5	ApexBio	5 mg	EUR 110

JW 480
B5556-50	ApexBio	50 mg	EUR 540

Sulforhodamine 101 sulfonyl chloride [Texas Red®] *CAS 82354-19-6*
480	AAT Bioquest	10 mg	EUR 132

Mouse Sickle tail protein (SKT) ELISA Kit
abx389166-96tests	Abbexa	96 tests	EUR 911

Mouse Sickle tail protein, Skt ELISA KIT
ELI-29595m	Lifescience Market	96 Tests	EUR 865

RG 108
A1913-10	ApexBio	10 mg	EUR 119
Description: RG108 is a DNA methyltransferase (DMNT) inhibitor that enhanced reprogramming of OK-transduced MEFs in the presence of BIX. It is a small molecule that effectively blocked DNA methyltransferases in vitro and did not cause covalent enzyme trapping in human cell lines.

RG 108
A1913-25	ApexBio	25 mg	EUR 166
Description: RG108 is a DNA methyltransferase (DMNT) inhibitor that enhanced reprogramming of OK-transduced MEFs in the presence of BIX. It is a small molecule that effectively blocked DNA methyltransferases in vitro and did not cause covalent enzyme trapping in human cell lines.

RG 108
A1913-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 119
Description: RG108 is a DNA methyltransferase (DMNT) inhibitor that enhanced reprogramming of OK-transduced MEFs in the presence of BIX. It is a small molecule that effectively blocked DNA methyltransferases in vitro and did not cause covalent enzyme trapping in human cell lines.

RG 108
1679-10	Biovision		EUR 180

RG 108
1679-30	Biovision		EUR 359

Glucose M9Y
108	AthenaES	500 g	EUR 84

Human Sickle tail protein homolog, SKT ELISA KIT
ELI-18163h	Lifescience Market	96 Tests	EUR 824

Handheld Fluorometer 480/530nm
FL480530	BioAssay Systems	1 unit	EUR 1572
Description: Compact handheld fluorometer (exc.480 and em.530nm) for quantitative determination of various analytes in life sciences R&D, food safety and environmental monitoring. Highly sensitive, rapid-reading, reliable and low cost.

Angiogenin (108-122)
HY-P1516	MedChemExpress	10mg	EUR 980

Angiogenin (108-122)
5-00673	CHI Scientific	4 x 1mg	Ask for price

Angiogenin (108-123)
5-00674	CHI Scientific	4 x 1mg	Ask for price

Angiogenin (108-123)
H-8020.0001	Bachem	1.0mg	EUR 441
Description: Sum Formula: C83H132N26O24; CAS# [112173-48-5]

Angiogenin (108-123)
H-8020.0005	Bachem	5.0mg	EUR 1675
Description: Sum Formula: C83H132N26O24; CAS# [112173-48-5]

Angiogenin (108-122)
H-8095.0001	Bachem	1.0mg	EUR 212
Description: Sum Formula: C78H125N25O23; CAS# [112173-49-6]

Angiogenin (108-122)
H-8095.0005	Bachem	5.0mg	EUR 756
Description: Sum Formula: C78H125N25O23; CAS# [112173-49-6]

Skt ELISA Kit| Mouse Sickle tail protein ELISA Kit
EF014796	Lifescience Market	96 Tests	EUR 689

Anti-DDX41 (aa468-480) antibody
STJ73402	St John's Laboratory	100 µg	EUR 359

Polyclonal ADD3 Antibody (aa431-480)
APR14821G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ADD3 (aa431-480). This antibody is tested and proven to work in the following applications:

Acrp30 (108-244) Adiponectin (108-244 a.a.) Human Recombinant Protein
PROTQ15848-1	BosterBio	Regular: 25ug	EUR 317
Description: Acrp30 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (108-244 a.a.) and having a molecular mass of 18.1kDa.;Acrp30 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Angiogenin (108-122) (TFA)
HY-P1516A	MedChemExpress	10mM/1mL	EUR 1988

HIST1H2BC (Ab-108) Antibody
1-CSB-PA010403OA108nacHU	Cusabio	EUR 332.00 EUR 335.00	100ul 50ul
Description: A polyclonal antibody against HIST1H2BC (Ab-108). Recognizes HIST1H2BC (Ab-108) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

HIST1H2BC (Ab-108) Antibody
1-CSB-PA010403OA108nforHU	Cusabio	EUR 332.00 EUR 335.00	100ul 50ul
Description: A polyclonal antibody against HIST1H2BC (Ab-108). Recognizes HIST1H2BC (Ab-108) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IP; Recommended dilution: WB:1:200-1:2000, IHC:1:10-1:100, IP:1:200-1:2000

HIST1H2BC (Ab-108) Antibody
1-CSB-PA010403OA108nhibHU	Cusabio	EUR 332.00 EUR 335.00	100ul 50ul
Description: A polyclonal antibody against HIST1H2BC (Ab-108). Recognizes HIST1H2BC (Ab-108) from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, ChIP; Recommended dilution: WB:1:200-1:2000

Anti-IGKV1OR2-108 (3A11)
YF-MA20540	Abfrontier	100 ug	EUR 363
Description: Mouse monoclonal to IGKV1OR2-108

Zinc Finger Protein 480 (ZNF480) Antibody
20-abx116741	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Zinc Finger Protein 480 (ZNF480) Antibody
abx030192-400ul	Abbexa	400 ul	EUR 523

Zinc Finger Protein 480 (ZNF480) Antibody
abx030192-80l	Abbexa	80 µl	EUR 286

Polyclonal TAOK1 / TAO1 Antibody (aa431-480)
AMM08087G	Leading Biology	0.05ml	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TAOK1 / TAO1 (aa431-480). This antibody is tested and proven to work in the following applications:

Myosin Light Chain Kinase (480-501)
H-3554.0500	Bachem	0.5mg	EUR 273
Description: Sum Formula: C120H209N41O28S2; CAS# [313642-00-1]

Myosin Light Chain Kinase (480-501)
H-3554.1000	Bachem	1.0mg	EUR 466
Description: Sum Formula: C120H209N41O28S2; CAS# [313642-00-1]

SSEA-1 Antibody (Clone MC-480)
3063-25	Biovision		EUR 272

amfiSure PCR Premix, 8-Strip 0.2ml tube with Individual attached cap
P0316-480	GenDepot	5X96 rxns	EUR 529

amfiEco PCR Premix
P0702-480	GenDepot	5x96 rxns	EUR 444

amfiRivert 1-Step RT-PCR Premix
R5004-480	GenDepot	5x96 rxns	EUR 928

Recombinant (E.Coli, GST tag) Hepatitis C Virus (HCV) NS5 Genotype-4
RP-480	Alpha Diagnostics	100 ug	EUR 286

WST-1 Cell Proliferation Colorimetric Assay Kit
K2021-480	ApexBio	480 assays	EUR 321

TSLP (R127A, R130A) Recombinant Protein
11-480	ProSci	0.1 mg	EUR 595.25
Description: Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

IL-4 Recombinant Protein
90-480	ProSci	10 ug	EUR 364.25
Description: Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.

Reg1 alpha Recombinant Protein
91-480	ProSci	0.05 mg	EUR 542.75
Description: Regenerating Islet-Derived Protein 1- alpha (REG1A) belongs to the Reg family of secreted proteins with a C-type lectic domain. REG1A is highly expressed levels in fetal and infant brains, much lower in adult brains. REG1A promotes the maintenance and growth of pancreatic islet cells and intestinal villi. In addition to, REG1A Might act as an inhibitor of spontaneous calcium carbonate precipitation and be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

IL-2 R beta Recombinant Protein
92-480	ProSci	0.05 mg	EUR 684.5
Description: Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

Transmembrane Protein 108 (TMEM108) Antibody
20-abx116235	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Transmembrane Protein 108 (TMEM108) Antibody
abx034435-400ul	Abbexa	400 ul	EUR 523

Transmembrane Protein 108 (TMEM108) Antibody
abx034435-80l	Abbexa	80 µl	EUR 286

MHC I(108-2C5) Antibody
BNCA1095-250	Biotium	250uL	EUR 383
Description: Primary antibody against MHC I(108-2C5), APC conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC811095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF680R conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC811095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF680R conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCAP1095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCAP1095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCB1095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), Biotin conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCB1095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), Biotin conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC471095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF647 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC471095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF647 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC551095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF555 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC551095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF555 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC431095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF543 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC431095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF543 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC881095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF488A conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC881095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF488A conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC941095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF594 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC941095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF594 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCH1095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCH1095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNCP1095-250	Biotium	250uL	EUR 383
Description: Primary antibody against MHC I(108-2C5), PerCP conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC041095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF405S conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC041095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF405S conjugate, Concentration: 0.1mg/mL

Adiponectin (108-244 a.a.) Protein
20-abx261717	Abbexa	EUR 3530.00 EUR 328.00 EUR 230.00	1 mg 25 ug 5 ug

Transmembrane Protein 108 (TMEM108) Antibody
abx238746-100ug	Abbexa	100 ug	EUR 551

Recombinant ASFV War-108 Protein
VAng-1044Lsx-inquire	Creative Biolabs	inquire	Ask for price
Description: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) Virus attachment protein p12 (War-108), partial, recombinant protein from E. coli. (Uniprot ID: P0C9Y4)

Anti-mAPCS (aa97-108) antibody
STJ72695	St John's Laboratory	100 µg	EUR 260

Cytochrome c fragment (93-108)
A1062-1	ApexBio	1 mg	EUR 137
Description: H2N-ANERADLIAYLKQATK-OHTheCytochrome cis a smallhemeproteinfound loosely associated with the inner membrane of themitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1.

Cytochrome c fragment (93-108)
A1062-10	ApexBio	10 mg	EUR 485
Description: H2N-ANERADLIAYLKQATK-OHTheCytochrome cis a smallhemeproteinfound loosely associated with the inner membrane of themitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1.

Cytochrome c fragment (93-108)
A1062-25	ApexBio	25 mg	EUR 659
Description: H2N-ANERADLIAYLKQATK-OHTheCytochrome cis a smallhemeproteinfound loosely associated with the inner membrane of themitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1.

Cytochrome c fragment (93-108)
A1062-5	ApexBio	5 mg	EUR 311
Description: H2N-ANERADLIAYLKQATK-OHTheCytochrome cis a smallhemeproteinfound loosely associated with the inner membrane of themitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1.

MHC I(108-2C5) Antibody
BNCR1095-250	Biotium	250uL	EUR 383
Description: Primary antibody against MHC I(108-2C5), RPE conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNUB1095-100	Biotium	100uL	EUR 209
Description: Primary antibody against MHC I(108-2C5), Concentration: 0.2mg/mL

MHC I(108-2C5) Antibody
BNUB1095-500	Biotium	500uL	EUR 458
Description: Primary antibody against MHC I(108-2C5), Concentration: 0.2mg/mL

MHC I(108-2C5) Antibody
BNC681095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF568 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC681095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF568 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC701095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF770 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC701095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF770 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC051095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF405M conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC051095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF405M conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC611095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF660R conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC611095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF660R conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC401095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF640R conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC401095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF640R conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC801095-100	Biotium	100uL	EUR 199
Description: Primary antibody against MHC I(108-2C5), CF680 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNC801095-500	Biotium	500uL	EUR 544
Description: Primary antibody against MHC I(108-2C5), CF680 conjugate, Concentration: 0.1mg/mL

MHC I(108-2C5) Antibody
BNUM1095-50	Biotium	50uL	EUR 395
Description: Primary antibody against MHC I(108-2C5), 1mg/mL

EZSolution? RG-108, Sterile-filtered
B2238-5	Biovision		EUR 196

IGKV1OR2-108 Recombinant Protein (Human)
RP065016	ABM	100 ug	Ask for price

Recombinant Rat Akt1 Protein (aa 1-480)
VAng-2932Lsx-1mg	Creative Biolabs	1 mg	EUR 5590
Description: Recombinant Rat Akt1 is expressed in E. coli. (Uniprot ID: P47196)

Recombinant Rat Akt1 Protein (aa 1-480)
VAng-2932Lsx-200g	Creative Biolabs	200 µg	EUR 3363
Description: Recombinant Rat Akt1 is expressed in E. coli. (Uniprot ID: P47196)

Recombinant Rat Akt1 Protein (aa 1-480)
VAng-2932Lsx-50g	Creative Biolabs	50 µg	EUR 2525
Description: Recombinant Rat Akt1 is expressed in E. coli. (Uniprot ID: P47196)

Recombinant Mouse Akt1 Protein (aa 1-480)
VAng-2933Lsx-1mg	Creative Biolabs	1 mg	EUR 5590
Description: Recombinant Mouse Akt1 is expressed in E. coli. (Uniprot ID: P31750)

Recombinant Mouse Akt1 Protein (aa 1-480)
VAng-2933Lsx-200g	Creative Biolabs	200 µg	EUR 3363
Description: Recombinant Mouse Akt1 is expressed in E. coli. (Uniprot ID: P31750)

Recombinant Mouse Akt1 Protein (aa 1-480)
VAng-2933Lsx-50g	Creative Biolabs	50 µg	EUR 2525
Description: Recombinant Mouse Akt1 is expressed in E. coli. (Uniprot ID: P31750)

Protein-A ELISA Kit, 480 tests, Quantitative
800-110-PRA-5	Alpha Diagnostics	1 pk	EUR 3095

Recombinant MARV nifE (aa 1-480) Protein
VAng-Wyb3541-1mgEcoli	Creative Biolabs	1 mg (E. coli)	EUR 5247
Description: Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) nitrogenase iron-molybdenum cofactor biosynthesis protein NifE, recombinant protein.

Recombinant MARV nifE (aa 1-480) Protein
VAng-Wyb3541-500gEcoli	Creative Biolabs	500 µg (E. coli)	EUR 3707
Description: Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) nitrogenase iron-molybdenum cofactor biosynthesis protein NifE, recombinant protein.

Recombinant MARV nifE (aa 1-480) Protein
VAng-Wyb3541-50gEcoli	Creative Biolabs	50 µg (E. coli)	EUR 2525
Description: Methanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) nitrogenase iron-molybdenum cofactor biosynthesis protein NifE, recombinant protein.

Opti-Seal qPCR Roche 480 (Low profile)
G913	ABM	100 Plates/Case	EUR 302

Opti-Seal qPCR Roche 480 (Low profile)
G914	ABM	10 Plates/Box	EUR 76

Mouse Olfactory receptor 480, Olfr480 ELISA KIT
ELI-14769m	Lifescience Market	96 Tests	EUR 865

Recombinant Human Complement Factor D Protein-His-GST tag
CTP-108	Creative Biolabs	100ug	Ask for price
Description: A 59 kDa recombinant human Complement Factor D protein with a N-terminal His and GST tag expressed in E. Coli.

CytoSelect 24-well Cell Migration Assay (12 ?m), Fluorometric
CBA-108	Cell Biolabs	12 assays	EUR 566
Description: Chemotaxis describes the movement of cells toward or away from a chemical stimulus in their enviroment. Cell chemotaxis plays a pivotal role in the progression of cancer and other diseases. CytoSelect Cell Migration Assays are ideal for determining the chemotactic properties of cells. The 12 µm pore size is suitable for astrocytes and other large or slow-moving cells.

SIDEARM FITTING, SENSOR, O2 PROBES
4519-108	CORNING	1/pk	EUR 200
Description: Bioprocess Vessels; Spinner Accessories

Universal Casein Diluent/Blocker
85R-108	Fitzgerald	250 ml	EUR 230
Description: Ready-to-use biotin free reagent applicable for blocking ELISA plates

CD14 Recombinant Protein
96-108	ProSci	0.1 mg	EUR 516.5
Description: Cluster of differentiation 14 (CD14), is a cell surface glycoprotein, and is a is a component of the innate immune system. CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists in two forms. Either it is anchored into the membrane by a glycosylphosphatidylinositol tail (mCD14) or it appears in a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa). CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. CD14+ cells are monocytes that can differentiate into a host of different cells. CD14 has been shown to interact with Lipopolysaccharide-binding protein.

Heart Ventricle (RT) Lysate
20-108	ProSci	0.1 mg	EUR 416.75
Description: Human heart right ventricle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human heart right ventricle tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the heart right ventricle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The heart right ventricle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

SARS-CoV-2 (COVID-19) S1+S2 ECD (S-ECD) Recombinant Protein
10-108	ProSci	0.1 mg	EUR 989
Description: The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses as well as protective immunity.

SARS Coronavirus Spike Recombinant protein (1-53, 90-115, 171-205 aa)
39-108	ProSci	0.05 mg	EUR 464
Description: SARS Associated Coronavirus Spike is a causative agent of SARS virus. Diseases caused by Coronaviruses are usually controlled by CD8 T cells. The spike antigen is one of the main surface proteins on Coronavirus, therefore one of the main proteins that are candidates for vaccines.

beta-Defensin 1 Recombinant Protein
91-108	ProSci	0.05 mg	EUR 542.75
Description: beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.

CaM Kinase II Subunit Beta Recombinant Protein
92-108	ProSci	0.05 mg	EUR 710.75
Description: Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta (CAMK2B) is a cytoplasmic protein that belongs to the serine/threonine protein kinase family and the Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2B is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplamic reticulum Ca2+ transport in skeletal muscle. In neurons, CAMK2B plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.

CFTR (108-117), Pseudomonas aeruginosa Inhibitor
5-00965	CHI Scientific	4 x 5mg	Ask for price

Polyclonal MAGE12 / MAGEA12 Antibody (aa96-108)
APR02325G	Leading Biology	0.05mg	EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MAGE12 / MAGEA12 (aa96-108). This antibody is tested and proven to work in the following applications:

Recombinant HBV PreS1 (aa 1-108)
VAng-Lsx0186-1mg	Creative Biolabs	1 mg	EUR 3648
Description: HBV PreS1 (aa 1-108), recombinant protein from E. coli.

Human Angiogenin 108-123 aa peptide
ANGN108-P	Alpha Diagnostics	1 mg	EUR 286

IGKV1OR2-108 ORF Vector (Human) (pORF)
ORF021673	ABM	1.0 ug DNA	Ask for price

DISH,100X20MM,TCT,PS,S,BK,10/480
430293	CORNING	10/pk	EUR 305
Description: Lab Cell Culture; Corning TC Dishes

Recombinant ASFV Ken-089 Protein (aa 1-480)
VAng-2098Lsx-1mg	Creative Biolabs	1 mg	EUR 5728
Description: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) Uncharacterized protein B475L (Ken-089), partial, recombinant protein from E. coli. (Uniprot ID: P0CAH7)

Recombinant ASFV Ken-089 Protein (aa 1-480)
VAng-2098Lsx-500g	Creative Biolabs	500 µg	EUR 3528
Description: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) Uncharacterized protein B475L (Ken-089), partial, recombinant protein from E. coli. (Uniprot ID: P0CAH7)

Recombinant Treponema Pallidum atpB2 Protein (aa 1-480)
VAng-Cr1481-1mgEcoli	Creative Biolabs	1 mg (E. coli)	EUR 5198
Description: Treponema Pallidum (strain Nichols) v-type ATP synthase beta chain 2 (atpB2), recombinant protein.

Recombinant Treponema Pallidum atpB2 Protein (aa 1-480)
VAng-Cr1481-500gEcoli	Creative Biolabs	500 µg (E. coli)	EUR 3712
Description: Treponema Pallidum (strain Nichols) v-type ATP synthase beta chain 2 (atpB2), recombinant protein.

Recombinant Treponema Pallidum atpB2 Protein (aa 1-480)
VAng-Cr1481-50gEcoli	Creative Biolabs	50 µg (E. coli)	EUR 2530
Description: Treponema Pallidum (strain Nichols) v-type ATP synthase beta chain 2 (atpB2), recombinant protein.

Recombinant Pseudomonas Aeruginosa murC Protein (aa 1-480)
VAng-Cr0561-1mgEcoli	Creative Biolabs	1 mg (E. coli)	EUR 5502
Description: Pseudomonas Aeruginosa (strain PA7) UDP-N-acetylmuramate--L-alanine ligase (murC), recombinant protein.

Recombinant Pseudomonas Aeruginosa murC Protein (aa 1-480)
VAng-Cr0561-500gEcoli	Creative Biolabs	500 µg (E. coli)	EUR 3724
Description: Pseudomonas Aeruginosa (strain PA7) UDP-N-acetylmuramate--L-alanine ligase (murC), recombinant protein.

Recombinant Pseudomonas Aeruginosa murC Protein (aa 1-480)
VAng-Cr0561-50gEcoli	Creative Biolabs	50 µg (E. coli)	EUR 2530
Description: Pseudomonas Aeruginosa (strain PA7) UDP-N-acetylmuramate--L-alanine ligase (murC), recombinant protein.

Protein-G (HCPs) ELISA Kit, 480 tests, Quantitative
800-120-PRG-5	Alpha Diagnostics	1 pk	EUR 3095